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Relevance of Glucagon Like Peptide 1 (GLP 1) in Inflammatory Bowel Diseases: A Narrative Review As insurers struggle with GLP 1 drug costs, some seek to wean patients off ABC News Stars Who've Spoken About Ozempic for Weight Loss (and What They've Said) What happens when you stop weight loss drugs like GLP 1 injections? The answer is not as simple as you gain it all back. A study published in Diabetes, Obesity and Metabolism analysed 7,938 My personal GLP 1 maintenance insights You may have heard that GLP 1 medications like Ozempic could affect how long Botox lasts. A recent simulation study suggests results may soften a few weeks earlier in some patients. While this
:max_bytes(150000):strip_icc():focal(959x332:961x334)/dolores-catania-ozempic-040523-4af36963b2a94ddabedce20ebbedbfee.jpg "Stars Who've Spoken About Ozempic for Weight Loss (and What They've Said)")
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png "Mechanism of action of GLP-1 [25]")
Best in 7 days
4.6 ★★★★★
Based on 1956 reviews
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Product Reviews
★★★★★ 5
Great Vacuum
Configuration: Vacuum
I've had my vacuum for several months now. It is fantastic on hardwood floors and does a great job on furniture and stairs. The vacuum is very lightweight and quiet, making it easy to use in our two story, open plan house. Previously, I would get dirty looks from my husband if I tried to run the vacuum upstairs while he was watching television in the living area. I first purchased a Miele C1 series vacuum last year to replace my upstairs vacuum. I love that vacuum, but it has limitations as far as doing area rugs and carpet. My previous vacuums have all been Kenmore canister vacuums, and that was the only brand I would buy. I gave the Miele C1 a chance when Amazon had it at a special price. I then purchased this model, the C3, after several months because the vacuum I used downstairs started having issues. This vacuum is so lightweight and easy to carry up and down stairs that I probably should have splurged on the C3 model to begin with, as I almost always end up carrying the C3 upstairs to do the carpet in the bedroom anyway. My previous Kenmore canister vacs were very heavy and were almost impossible for me to carry safely on the stairs. While the C1 has attachments that are on a very poorly designed holder that is supposed to clip on the hose (doesn't stay there), this model has attachments inside the canister making them much more accessible and safe from being lost.
My biggest complaint about this vacuum is the power brush. I have 6 cats - 3 long-haired rescues and 3 Maine Coon cats. If you are familiar with Maine Coon breed, you know they are all about fur, lots and lots of fur. We have to do a lot of brushing in our house, and our vacuums have to work hard. I discovered that the power brush is quickly overpowered with cat fur sticking on the roller brush, and I need to take small scissors after every use on a carpet and remove all the fur before the next use. It is a tedious chore and I can't believe a vacuum at this price point doesn't have a better power brush design. It does a good job cleaning the carpets, but you do have to keep after the cleaning of the brush roller. I did not have to do that with my Kenmore turbo brush. Thankfully, we only have 2 carpeted rooms in our house, and a few area rugs, so mostly I am vacuuming hardwood and it does a fantastic job on that.
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Reviewed in the United States on April 15, 2019
★★★★★ 5
Best cleaning Investment you can make
Configuration: Vacuum
I have Dyson to thank for this purchase. I wanted a quiet, light, high quality vacuum that was reputable and highly rated. I had the Dyson V8 which was only really useful in the high settings, aka 7 min run time. Unless you have the patience going over the same area in the low setting. I found this vacuum through many good reviews, recommendations and a feature on a USA today article. I was hesitant spending that much money on a vacuum but after seeing how much I cleaned with a quiet vacuum in the Dyson V8 ( which I ended up returning), I made the plunge. Being able to pay the 5 installment payments on Amazon really helped make the purchase easier as well 😬.
Things I really liked about the Vacuum:
Its quiet. Coming from an old upright, I'm surprised how I can vacuum at midnight and not worry about the noise.
Its light. You're just using the light hose while the unit rolls behind you. Makes vacuuming blinds super easy. The Dyson V8 was a chore at this. The whole unit itself is really light too, where I notice I vacuum my truck more than usual now days.
Its powerful. Don't let the low sound fool you, I compared this with my Old Eureka upright vacuum and couldn't believe the suction was the same!
Things I would like improved:
Distinguishing Buttons for the bottom Power and Cord retract. I put blue painters tape on the cord retract button to make it quickly identifiable.
More modern Hardwood floor brush. Maybe one like the Dyson soft rolling brush?
Better Bag Fully indicator. Indicator basically throws you off because it goes by the resistance of the suction. So when you're vacuuming floors to even using the small brush attachment, it keeps going wild.
Other than those small gripes, I REALLY LOVE THIS VACUUM! While cordless vacuums seems to be the trend now days, I prefer the stable reliable power of the cord. Having the retractable cord button really helps too. And although I like how bagless vacuums let you monitor how much dirt you're sucking up, the clean up of bagged vacuums are a lot less messier. But to each their own. I highly recommend this Unit!
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Reviewed in the United States on June 25, 2018
★★★★★ 5
Miele
Configuration: Vacuum
Best vacuum ever! Great performance for all floors. Durable and powerful. Highly recommended.
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Reviewed in the United States on April 23, 2026
★★★★★ 5
Keeps ALL it's promises
Configuration: Vacuum
12/27/18 I have been using this vac over a year to clean our home's hardwood and vinyl floors and low pile area rugs. Disclaimer: we are not related to the company in any way, shape or form - have to say that because this review may sound like a commercial! This vacuum is small, quiet, very powerful and fulfills every promise the company makes about it. This unit comes with 3 small tools contained in the unit, 1 hard floor tool (vacuum powered) and 1 low pile carpet tool (vacuum powered). The 2 floor tools clip onto the sides of the canister. There are 6 power settings from a low for drapes to a high for hardwood floors, all marked with an icon. The power cord IS EXTRA LONG - yes, fewer plug changes - and the re-tractor works beautifully (I do let the cord slid through my fingers and catch the plug end to keep it from slamming into the back out of habit). The wand section is collapsible, which I just thought was nice for storage until I began using that feature while vacuuming in tight spaces, where you can change the wand length on the fly. The floor tools' articulated connection to the hose looks quirky until you begin using it; it makes the tool head extremely nimble in getting into tight spaces. The hard floor head has a skip tooth brush pattern around the edge which pulls in dust instead of pushing dust in front of it. The suction works all the way out to the ends - it will pull dust into the head from ALL the way around. The dust bag and separate HEPA filter have markers to let you know when to change them. I haven't changed either yet (note: we do not have pets, the house is vacuumed weekly). It tracks easily and the side bumper strips are placed where they actually work!
Problems? well it is expensive, but I don't see replacing it any time soon.
Seriously, I am still amazed at how well built and well thought out this unit is.
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Reviewed in the United States on December 27, 2018
★★★★★ 1
I absolutely hate this vacuum.
Configuration: Vacuum
I bought it due to the positive reviews and was tired of my Dyson ball vacuum. Since day one I have had nothing but problems with a vomit like smell that comes out of this vacuum every time we use it. It got to the point that we have replaced the filter with expensive carbon filters, washed out the hoses and attachments with bleach, and nothing has worked to get this thing to smell better. To make matters worse, the suction power of this thing is limited at best compared to other vacuums we have owned. I can go over the carpet with my old Dyson and pick up a significant amount of dirt that the miele cannot even come close to getting. I wish I had returned it when I still had a chance.
We have now bought a iRobot Roomba 980 and honestly it is 100x better than the Miele piece of junk that just sits in the closet now. It has strong suction power, is easier to clean, and keeps the house clean.
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Reviewed in the United States on January 21, 2019
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